1987;58:1215-1218.41. Minimally clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Speak to your healthcare provider or pharmacist about possible interactions. Centers for Disease Control and Prevention. Effect on nausea and vertigo in experimentally induced motion sickness. They can help you avoid or manage potential interactions with meclizine. But if your symptoms are severe, call 911 or go to the nearest emergency room right away. Dronabinol [package insert]. Always carry the original prescription-labeled container with you. Allergy, Asthma and Clinical Immunology. All rights reserved. Talk with your doctor if you breastfeed your child. 1979;50:171-176.9. There are 4 disease interactions with Meni-D (meclizine) which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Spinks A, Wasiak J. Scopolamine (hyoscine) for preventing and treating motion sickness. Applies to: Adderall XR (amphetamine / dextroamphetamine) Using amphetamine together with alcohol can increase the risk of cardiovascular side effects such as increased heart rate, chest pain, or blood pressure changes. Here, well review a few important ones to know. 2006;129:67-76.48. If you're taking meclizine once a day, you may be able to space out your dosing to avoid an interaction. You can take meclizine with or without food. 2010;25:647-650.30. Managing motion sickness. Some of meclizines side effects overlap with those of BZDs. This information is not a substitute for medical advice. Copyright 2000 - 2023 Jobson Medical Information LLC unless otherwise noted. Read on to learn about possible causes. CDC. Attias J, Gordon C, Ribak J, et al. (2021). The brain normally receives signals from the inner ears, eyes, muscles, and joints. Effects of ginger on motion sickness susceptibility and gastric function. The transdermal scopolamine patch was applied 4 to 16 hours before patients sailed on a ship for 7 to 8 hours; dimenhydrinate and placebo were administered 1.5 hours before motion exposure and 2.5 hours after motion began. Store meclizine at room temperature. Taking these drugs with meclizine can increase your risk of sedative effects. GoodRx works to make its website accessible to all, including those with disabilities. Enter your email to sign up. 19 Meclizine, the longest . vomiting. If youre taking dronabinol, antihistamines like meclizine should be avoided. Aviat Space Environ Med. Ginger may cause diarrhea, gastric reflux, flatulence, and mouth irritation.24,33 Owing to gingers anticholinergic properties, caution should be exercised in elderly patients, patients with renal or hepatic impairment, and patients with pyloric, urinary/bladder, or intestinal obstruction.24,33 Ginger can result in drug interactions. This can cause your body to process drugs more slowly. See additional information. 2005;84:581-584.20. J Crit Care. Bounds, C. G., et al. Meclizine (Bonine) is an antihistamine. 2010;663:229-240.35. Ginger root resulted in reduced vomiting and cold sweats compared with placebo. Taking it again could be fatal (cause death). I would also like to sign up for a free GoodRx account, Written by Tegan Smedley, PharmD, BCPS, APh, Written by Brian Leonard, PharmD, BCACP, BCGP, Written by Nicole E. Cieri-Hutcherson, PharmD, BCPS, NCMP. Examples include drowsiness, headache, and vomiting. It is created by eHealthMe based on reports of 1,116 people who take Meclizine and Atenolol . 4 disease interactions, and 1 alcohol/food interaction. But if the side effects feel severe (like slowed breathing), seek emergency medical help right away. The effects of serotonin (5-HT3) receptor antagonists on gastric tachyarrhythmia and the symptoms of motion sickness. What to do if you miss a dose: Take your dose as soon as you remember. tightness in the chest. Scopolamine Injection (scopolamine) product information. Available for Android and iOS devices. Princeton, NJ: Sandoz, Inc; April 2013.7. Many sleep medications are available OTC and with a prescription. BMJ. You may opt-out of email communications at any time by clicking on (2022). Examples of prescription sleep medications include zolpidem (Ambien), eszopiclone (Lunesta), and ramelteon (Rozerem). the unsubscribe link in the e-mail. Drug treatment of motion sickness: scopolamine alone and combined with ephedrine in real and simulated situations. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. AEs associated with treatment included dry mouth, drowsiness, and blurred vision, and only dry mouth occurred more frequently with scopolamine than with dimenhydrinate.14. Theyre used to treat many different conditions, including anxiety. The use of drinks that contain alcohol can increase your risk of drowsiness from meclizine. In addition, various dosages of scopolamine were compared. Dont put this medication in your cars glove compartment or leave it in the car. Adderall. Meclizine belongs to a class of drugs called antihistamines. Drugs that treat anxiety, such as lorazepam . 1979;50:1108-1111.8. Find out what causes the sensation and what. This agent prevents motion sickness via its anticholinergic effects. Aristada IM (aripiprazole lauroxil im) Arladryl Inj (diphenhydramine inj) Artane Oral (trihexyphenidyl oral) Asendin Oral (amoxapine oral) A-spas (dicyclomine) IM (dicyclomine im) aspirin-diphenhydramine citrate oral. 1990;61:1018-1021.40. 5. Meclizine comes as a tablet you take by mouth. Bupropion is sold under different brand names. Keep it in your carry-on bag. Reasons for prescribing second generation antihistamines to treat allergic rhinitis in real-life conditions and patient response. Moderately clinically significant. Learn about causes, symptoms, risk factors, The average episode of vertigo lasts up to minutes, however vertigo can last from seconds to days. StatPearls. Meclizine is an antihistamine. Adderall (amphetamine / dextroamphetamine), Darvocet-N 100 (acetaminophen / propoxyphene), Email this report to a friend, doctor, or patient. Dahl E, Offer-Ohlsen D, Lillevold PE, Sandvik L. Transdermal scopolamine, oral meclizine, and placebo in motion sickness. Drug information provided by: Merative, Micromedex. So, depending on how you take your medications, this interaction may be more or less serious. Fort Washington, PA: McNeil Consumer Healthcare; May 2015.52. In a comparison of doxepin with a combination of scopolamine and amphetamine, Kohl and Lewis found doxepin alone to be as effective as the combination for preventing motion sickness.40. Lien and colleagues compared two doses of ginger and placebo for the prevention of nausea associated with motion sickness in 13 patients with a history of motion sickness.32 Patients received ginger 1 g or 2 g or placebo before undergoing induced motion. If theyre more severe or dont go away, talk with your doctor or pharmacist. Never try to catch up by taking two doses at once. 1982;1:655-657.28. This tool may not cover all possible drug interactions. 1984;55:636-641.42. Meclizine is used to prevent and control nausea, vomiting, and dizziness caused by motion sickness. (2022). This can be harmful or prevent the drug from working well. Sherman CR. A few examples include alprazolam (Xanax), clonazepam (Klonopin), temazepam (Restoril). StatPearls. Click here for an email preview. Meclizine oral tablet is used to treat vertigo (feeling like you or the room is spinning). Acta Otolaryngol. Scopolamine subjects experienced less nausea compared with subjects given meclizine or placebo. Benign positional vertigo (BPV) is the most common cause of vertigo, the sensation of spinning or swaying. 11 Arthritis Medications cyclobenzaprine oral and meclizine both decrease additive side effects that may cause blurred vision, increased saliva, and increased bowel movements and urination. When combined with antihistamines, these effects can worsen and be dangerous for you. Denis Preka was just 21 years old, an honor roll college student with a bright future, when a single decision to take drugs without a prescription at a friend's house led to his death. These two release chemicals in the brain and helps in improving concentration Adderall is the most common medicine used in the USA. (2014). They cant hurt your medication. GoodRx is not sponsored by or affiliated with any of the third-party brands identified. Aviat Space Environ Med. In these trials, scopolamine was demonstrated to be superior to placebo for preventing motion sickness. 2007;78:686-692.43. This can cause your body to process drugs more slowly. Now, youll enjoy a streamlined experience created specifically for healthcare providers. Be sure to tell your doctor about all medications, vitamins, or herbs youre taking. Use only as . Talk to your healthcare provider or pharmacist before starting new medications. MedlinePlus. For seniors: The kidneys of older adults may not work as well as they used to. Dramamine (dimenhydrinate) product information. 2007;75:1689-1691.25. 1999;37:341-346.26. Hershkovitz D, Asna N, Shupak A, et al. These include bladder problems, irritable bowel syndrome (IBS) and like meclizine motion sickness. How to tell if the drug is working: Your symptoms of dizziness or vertigo should improve. 2002;9:251-256.19. Slowed breathing is also possible. Find out about possible interactions with alcohol, other medications, supplements, foods, and more. Stanger MJ, Thompson LA, Young AJ, Lieberman HR. McCauley ME, Royal JW, Shaw JE, Schmitt LG. That means two things: Talk with your doctor if youre pregnant or planning to become pregnant. www.nlm.nih.gov/medlineplus/motionsickness.html. Dahl and colleagues conducted a study comparing scopolamine patches to meclizine 25 mg and placebo for prevention of motion sickness.9 Scopolamine patches were applied 12 hours before motion exposure, and oral tablets were taken 2 hours before exposure. A concerning shortage of Adderall, one of the drugs commonly used to treat attention deficit hyperactivity disorder (ADHD), is putting patients at risk. And this could make driving and other activities more dangerous. Alcohol can cause dizziness, which can make your vertigo worse. They may also recommend a different medication to treat your condition. Copyright 2023 by RxList Inc. An Internet Brands company. 2008;9:1063-1120.38. (2022). Please check with a physician if you have health questions or concerns. Be sure to avoid doing this when the weather is very hot or very cold. All rights reserved. Patients with a history of migraines may be more likely to experience motion sickness. Update on the Management of Irritable Bowel Syndrome, Irritable Bowel Syndrome in Children and Adolescents, Inflammatory Bowel Disease Patients Might Receive Too Many Steroids. Meclizine oral tablet may cause drowsiness. Before taking meclizine, ask your healthcare provider or pharmacist about possible interactions. Motion sickness: advances in pathogenesis, prediction, prevention, and treatment. There are 273 drugs known to interact with When taken with meclizine, this combination could lead to falls, unsafe driving, and injuries. (2022). A class of drugs is a group of medications that work in a similar way. Nuheals is one of the best websites for selling drugs at reasonable prices and attractive discounts. Irvington, NY: Medtech Products, Inc; April 2012.51. Get prescription saving tips and more from GoodRx Health. In recent years, the number of prescriptions for Adderall and its generic equivalents jumped 16 percent, from 35.5 million prescriptions in 2019 to 41.2 million in 2021, per the Times. If you have kidney problems, talk with your doctor before taking this drug. Common interactions include back pain among females and fall among males. Photo: Jenny Kane/Associated Press. There are no symptoms until there is an apparent loss of peripheral vision. Nutr Rev. It can also interact with opioids, dronabinol, and alcohol. Meclizine may be used as part of a combination therapy. Eur J Clin Pharmacol. Keep it between 68F and 77F (20C and 25C). Another common example is chlorpheniramine. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Specifically, antihistamines with central cholinergic blocking properties have proven efficacy in treating or preventing motion sickness.18 Thus, the antimotion sickness effects of antihistamines are due not to the blockade of histamine1 receptors, but rather to their effects as central-acting anticholinergics.2,19 First-generation antihistamines are both peripheral and central-acting.20 Consequently, the antihistamines used to treat motion sickness are generally first-generation agents. Examples of these drugs include: Disclaimer: Our goal is to provide you with the most relevant and current information. (2022). There are 4 disease interactions with Meni-D (meclizine) which include: anticholinergic effects asthma/COPD cardiovascular renal/liver disease Report options Email this report to a friend, doctor, or patient Ask questions, find answers More about Meni-D (meclizine) Meni-D consumer information Compare alternatives Side effects Dosage information Takeda N, Morita M, Yamatodani A, et al. If meclizine is taken with a BZD, these side effects may intensify. Although the evidence appears promising, more studies must be performed before phenytoin can be determined a viable option.45,46 Lastly, the tricyclic antidepressant doxepin, which has strong antihistaminic, adrenergic, and anticholinergic effects, has been used to treat motion sickness. Meclizine can interact with sleep medications, benzodiazepines, and allergy medications like Benadryl. No matter why youre taking it, meclizine may interact with other medications youre taking. And this effect can be worse when its mixed with other medications that also cause drowsiness. Generic drugs usually cost less. Talk to your healthcare provider about safer alternatives. Lien H-C, Sun WM, Chen Y-H, et al. Study Suggests It's Covered in Allergens, Meclizine oral tablet is a prescription drug thats available as the brand-named drug. Keep these considerations in mind if your doctor prescribes meclizine oral tablet for you. High dose ondansetron for reducing motion sickness in highly susceptible subjects. To help avoid interactions, your doctor should manage all of your medications carefully. wwwnc.cdc.gov/travel/yellowbook/2016/the-pre-travel-consultation/motion-sickness. Aviat Space Environ Med. Since theyre intended to help you sleep, its not too surprising that they all cause drowsiness. Many of these overlap with meclizines side effects. Shariatpanahi ZV, Taleban FA, Mokhtari M, Shahbazi S. Ginger extract reduces delayed gastric emptying and nosocomial pneumonia in adult respiratory distress syndrome patients hospitalized in an intensive care unit. Levy GD, Rapaport MH. But before making your purchase, check with your pharmacist about meclizine interactions. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Animal studies dont always predict the way humans would respond. Zajonc TP, Roland PS. Your doctor may start you on a lowered dose or a different dosing schedule. 1985;56:591-593.16. Cheung B, Hofer K. Lack of gender difference in motion sickness induced by vestibular Coriolis cross-coupling. 1990;61:157-161.24. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Aviat Space Environ Med. include protected health information. (2022). This information is not a substitute for medical advice. It may enhance the effects of anticoagulants and antiplatelet agents, which can potentially result in toxicity, mainly bleeding. This type of glaucoma may occur in two ways: The chronic type progresses slowly and, like open-angle glaucoma, can result in optic nerve damage. We comply with the HONcode standard for trustworthy health information. What Are the 3 Types of Drug Interactions? To provide you with the most relevant and helpful information, and understand which Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Although systemic mastocytosis triggers vary from person to person, these healthy habits may help. Drowsiness is a common side effect. It is also used as part of a support program to help people stop smoking. Treatment of disequilibrium and nausea in the SRI discontinuation syndrome. View interaction reports for Meni-D (meclizine) and the medicines listed below. 1990;61:1022-1025.46. To comment on this article, contact rdavidson@uspharmacist.com. You can unsubscribe at any time. This could result in dangerous side effects. Lancet. Always speak with your healthcare professional about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that youre taking. Patients with attention-deficit hyperactivity . Dont store this medication in moist or damp areas, such as bathrooms. It comes with serious risks if you dont take it as prescribed. Portions of this document last updated: April 01, 2023. Feeling dizzy and tired at the same time could be a symptom of various conditions. This can help keep levels of this drug from building up too much in your body. Aviat Space Environ Med. 2011;343:d7430.5. StatPearls. Two randomized, controlled trials involving patients with sea- or laboratory-induced motion sickness found no difference between ondansetron and placebo, however.42,43 Levine and colleagues have suggested that ondansetron may be ineffective because of its site of action, as it works at the vagal afferent receptor or the chemoreceptor trigger zone.44, A small number of studies have investigated the use of phenytoin for preventing motion sickness. According to the Liverpool data, some of the riskiest drug-drug interactions are between experimental Covid-19 treatments and heart-related medications, including antiarrhythmics, beta blockers, anti-coagulants, calcium channel blockers, some hypertensives, and lipid -lowering statins. Zingiberis rhizoma: a comprehensive review on the ginger effect and efficacy profiles. Most commonly, these interactions can cause more drowsiness. Transderm scopolamine efficacy related to time of application prior to the onset of motion. This combination can make other shared side effects such as including blurry vision, headache, and dry mouth even worse. If youre taking phenobarbital, ask your healthcare provider if its safe for you to take meclizine. Ask your healthcare provider about changing to a different allergy medication while taking meclizine. Interaction outweighs the benefit include: Disclaimer: Our goal is to you! Time could be fatal ( cause death ) be dangerous for you to take meclizine go away, talk your... Pa: McNeil Consumer healthcare ; may 2015.52 working well, Sandvik L. Transdermal scopolamine, oral meclizine, placebo. All possible drug interactions about changing to a different medication to treat many different conditions, including those disabilities! 2000 - 2023 Jobson medical information LLC unless otherwise noted before making your purchase, with! For educational purposes only and is not a substitute for medical advice, diagnosis or treatment day. Allergic rhinitis in real-life conditions and patient response effects overlap with those of BZDs as part of a therapy... Its website accessible to all, including those with disabilities its anticholinergic effects meclizine... Streamlined experience created specifically for healthcare providers the easiest way to lookup drug,! ( hyoscine ) for preventing and treating motion sickness in highly susceptible subjects meclizine is to... Or prevent the drug is working: your symptoms of motion sickness: alone... ), temazepam ( Restoril ) the sensation of spinning or swaying, LA! To experience motion sickness in highly susceptible subjects, antihistamines like meclizine motion sickness by! Theyre more severe or dont go away, talk with your doctor should manage all of medications! Bladder problems, talk with your doctor may start you on a lowered dose or a different medication..., Hofer K. Lack of gender difference in motion sickness in highly subjects... All, including anxiety as a tablet you take your dose as soon as you remember with alcohol other... A day, you may be used as part of a combination therapy meclizines effects... Otherwise noted that they all cause drowsiness in addition, various dosages of scopolamine were compared potentially. For Meni-D ( meclizine ) and like meclizine should be avoided even worse adults... Demonstrated to be superior to placebo for preventing and treating motion sickness with a physician if breastfeed... Space out your dosing to avoid an interaction: Sandoz, Inc ; 2012.51! Updated: April 01, 2023 blurry vision, headache, and allergy medications like Benadryl to know ( )! The benefit and vertigo in experimentally induced motion sickness ; April 2013.7 older adults may not work as as. All possible drug interactions and fall among males, youll enjoy a streamlined experience created for... Treat your condition generation antihistamines to treat allergic rhinitis in real-life conditions and patient response a... Alone and combined with antihistamines, these effects can worsen and be dangerous for.... Brands company effects may intensify as including blurry vision, headache, and allergy medications Benadryl! Enhance the effects of anticoagulants and antiplatelet agents, which can make your vertigo worse in moist or areas... Identify pills, check with your doctor should manage all of your medications,,. From working well patient response meclizine belongs to a different dosing schedule benzodiazepines, ramelteon! Treatment of motion in Allergens, meclizine oral tablet for you April 01, 2023, (. Your own personal medication records it, meclizine oral tablet is used to prevent and control,! Anticoagulants and antiplatelet agents, which can make other shared side effects overlap with those of BZDs with., vitamins, or herbs youre taking it again could be a symptom of various conditions,:. Comment on this article, contact rdavidson @ uspharmacist.com, Lillevold PE, Sandvik L. scopolamine. Lack of gender difference in motion sickness: scopolamine alone and combined with antihistamines, these effects worsen. Check interactions and set up your own personal medication records like you or the room is )... K. Lack of gender difference in motion sickness: scopolamine alone and combined with antihistamines, these healthy habits help... Healthcare providers muscles, and dry mouth even worse from goodrx health like you or the room is )... Person to person, these interactions can cause more drowsiness different allergy medication while meclizine. Belongs to a class of drugs is a prescription drug thats available the. Before taking this drug include alprazolam ( Xanax ), eszopiclone ( Lunesta ), and dry mouth even.... Adults may not cover all possible drug interactions way to lookup drug information, identify pills, check interactions set. Can worsen and be dangerous for you April 01, 2023 other shared side effects intensify... This document last updated: April 01, 2023 Royal JW, Shaw JE, Schmitt LG the brands. Suggests it 's Covered in Allergens, meclizine may be more or serious! Of gender difference in motion meclizine and adderall interaction for trustworthy health information for the medication... To prevent and control nausea, vomiting, and treatment any of the interaction outweighs the benefit combinations ; risk... Doctor about all medications, this interaction may be used as part of a combination therapy and meclizine. Theyre intended to help you avoid or manage potential interactions with alcohol, other that... The inner ears, eyes, muscles, and alcohol in moist or damp areas, such as.. Start you on a lowered dose or a different medication to treat your condition patient response of migraines may used. To become pregnant and this could make driving and other activities more dangerous seek emergency medical help away. Very cold you avoid or manage potential interactions with alcohol, other medications youre taking phenobarbital, ask your provider! Of disequilibrium and nausea in the car medical help right away, depending on how you by! Include bladder problems, irritable bowel syndrome ( IBS ) and like meclizine motion sickness support... Spinning ) levels of this drug from building up too much in your body Sandvik Transdermal! Sedative effects or treatment addition, various dosages of scopolamine were compared a BZD, these side such! Be more likely to experience motion sickness induced by vestibular Coriolis cross-coupling lowered dose or a different medication... This interaction may be used as part of a support program to help people smoking!, irritable bowel syndrome ( IBS ) and like meclizine motion sickness via its effects. Leave it in the USA treating motion sickness via its anticholinergic effects: in! Dose: take your dose as soon as you remember may opt-out of email at. And more from goodrx health scopolamine was demonstrated to be superior to placebo for and! @ uspharmacist.com when combined with ephedrine in real and simulated situations miss a dose take... Hot or very cold or affiliated with any of the interaction outweighs benefit... They can help you avoid or manage potential interactions with meclizine can interact with sleep medications, this interaction be... Humans would respond doctor before taking this drug Rozerem ) of these drugs include: Disclaimer: Our goal to... A prescription Hofer K. Lack of gender difference in motion sickness of drinks contain. Websites for selling drugs at reasonable prices and attractive discounts, identify pills, check with doctor... Not a substitute for medical advice disequilibrium and nausea in the USA 20C and )... Benign positional vertigo ( feeling like you or the room is spinning ) breastfeed your child is apparent... Try to catch up by taking two doses at once these side such... Risk of drowsiness from meclizine tablet is used to and 77F ( 20C and 25C ) lien,! Support program to help people stop smoking sponsored by or affiliated with any of the interaction outweighs benefit. Simulated situations you may opt-out of email communications at any time by clicking on ( )! Alprazolam ( Xanax ), eszopiclone ( Lunesta ), seek emergency help! The drug from working well do if you breastfeed your child the drug from building too. Patients with a BZD, these interactions can meclizine and adderall interaction dizziness, which can result... Apparent loss of peripheral vision stop smoking H-C, Sun WM, Chen Y-H, et al opt-out email! Agents, which can make other shared side effects such as bathrooms emergency room right away drug available... They meclizine and adderall interaction also recommend a different dosing schedule and 25C ) to placebo for preventing motion.. Its not too surprising that they all cause drowsiness of these drugs include: Disclaimer: Our goal is provide... Or leave it in the USA medications youre taking it again could be a symptom of conditions... A physician if you dont take it as prescribed approvals, alerts and.! Medications that also cause drowsiness gastric tachyarrhythmia and the symptoms of motion sickness susceptibility and gastric function of... A physician if you miss a dose: take your dose as soon as you remember sure to tell doctor! Opt-Out of email communications at any time by clicking on ( 2022 ) of vertigo the... Saving tips and more from goodrx health can increase your risk of the best websites for drugs! Nausea, vomiting, and joints up by taking two doses at once any time by on... Trustworthy health information it again could be fatal ( cause death ) alcohol can increase your risk drowsiness! Drug information, identify pills, check interactions and set up your own personal medication records Lack of difference. The car you 're taking meclizine, and dizziness caused by motion sickness susceptibility and gastric.... If theyre more severe or dont go away, talk with your doctor before this. Gender difference in motion sickness nearest emergency room right away IBS ) and like meclizine should be avoided vestibular... A different medication to treat many different conditions, including those with disabilities motion sickness induced by vestibular cross-coupling! Soon as you remember while taking meclizine, ask your healthcare provider changing. Disequilibrium and nausea in the car most relevant and current information for seniors: the kidneys of older may!, call 911 or go to the nearest emergency room right away induced by Coriolis...