So got it again. Retrieved from, Potts, J. The content on this site is for informational purposes only. Extremely strong winds called Santa Anas are possible. I was neutropenic with infection and just thought it was after effects of chemo. Dose levels 1, 2 and 3 (mg/m2 i.v.) I often feel like it's too much and want to give in. et al. So would recommend this. The drug can cause tear duct closures which can cause permanent tearing. Docetaxel injection is used to treat advanced or metastatic (cancer that has spread) breast cancer in patients who have previously received other cancer medicines that did not work well. Talk to your healthcare team for helpful tips on dealing with this side effect. Copyright: Merative US L.P. 1973, 2023. My concern is that with my weight, history of smoking and alcohol my body will not tolerate all of this. Include fiber in your diet (fruits and vegetables), drink 8-10 glasses of non-alcoholic fluids a day, and keep active. I have finished 4 cycles so far with 4 more to go. The 3rd week I just start to feel normal.and then whoops, time for another infusion to start the cycle. Retrieved from, Poi, M.J. et al. You have each cycle of treatment in the following way: Day 1 You have docetaxel as a drip into your Hi, not sure if my experiences will help you. Premedication reduced fluid retention with Taxotere by about 18%. Been told its best to as it helps the operation be morebsuccessful. Attorneys like those at Hotze Runkle can help right the wrongs the drug has caused. WebMarch 2009 #2. suggest new. WebMost patients tolerate Taxotere well. Dosages, drug combinations and drug responses will vary from patient to patient. This risk should be discussed routinely (as part of the process of informed consent) with all patients embarking upon docetaxel as a component of management of [early breast cancer].. These are some of the most common or important side effects: Allergic reactions are possible with this medication. It is also used together with cisplatin to treat advanced or metastatic NSCLC that cannot be removed by surgery in patients who have not received any cancer treatment for lung cancer. If mouth sores become painful, your doctor or nurse can recommend a pain reliever. Grapefruit can change how your body absorbs this medication. Taxotere docetaxel injection, solution, concentrate. So I feel that is a positive thought. You should let the oncology care team know if you experience numbness or tingling in the hands and/or feet, as they may need to adjust the doses of your medication. Edema happens when fluid collects under your skin and within the tissues outside your circulatory system. Taxotere is a strong chemotherapy drug that doctors prescribe to treat certain types of cancer. If you do not have a bowel movement for 2-3 days, you should contact your healthcare team for suggestions to relieve constipation. This may help delay symptoms from starting and may make them less severe if they do occur. Try to get up and about rather than stay in bed - it was better for me to keep as active as I could and just didn't do anything at all on the really low days. Docetaxel injection is also used to treat advanced or metastatic non-small cell lung cancer (NSCLC) in patients who have previously received platinum-based cancer medicines that did not work well. WebEach cycle of TC takes 21 days (3 weeks). But by my third week I felt somewhat normal, would tire quick but normal. (2014). From 2003 to June 2018, people reported to the FDA Adverse Events Reporting System (FAERS) a total of 21,037 adverse events related to the medication. Wear sunscreen (at least SPF 15) every day, wear sunglasses and long sleeves/pants to protect your skin. My skin, when I rub my fingers or touch my face, arms, legs etc feels different, almost plastic-y! The doctor's plan is for me to do the chemo, followed by radiation and then hormone suppressent pills for 5 years. Sorry there was an error. Last night she was saying that she doesn't know how she is going to get through the next treatment, especially since they supposedly get worse each time. I just had my first Docetaxal dose over a week ago.. Have you rang your chemo hotline? Keep people safe from potentially harmful drugs, medical devices and procedures by informing them of medical conditions, severe side effects and ways to take action. However, as required by the new California Consumer Privacy Act (CCPA), you may record your preference to view or remove your personal information by completing the form below. The most common chemotherapy drug for prostate cancer is docetaxel (Taxotere), which is usually given with prednisone, a steroid medicine. Different brand-name products contain varying amounts of alcohol. Your healthcare provider can recommend medications and other strategies to help relieve pain. Nights will be downright cold. It can be given alone or with other drugs. The information on this website is proprietary and protected. You may wear nail polish, but not fake nails. Heres a month by month breakdown: January: Temps are wildly inconsistent. Except she would always end up in hospital as her temp would spike along with the joint pains. Assisting patients and their families since 2008. Some can be more serious than others. Do Not Sell My Info. Men who are treated with this medication should use effective birth control during and for 4 months after the last dose. Does anyone have any suggestions of anything that can help me .. Tell your doctor about all the medicines you are currently taking and if you have problems with alcohol or other conditions that may be affected by ethanol in docetaxel. Severe reactions occurred in 3%-5% of patients with solid tumors and to a similar extent among metastatic breast cancer patients. Drug information provided by: Merative, Micromedex. No cancer cells were found, and she was deemed "no evidence of disease". Tell your doctor if you unusual tiredness or weakness. I wish I rang sooner. My experience was that how I felt after my following treatments was similar to my reaction after the first treatment. Studies show less than 10% of people who took docetaxel suffered the most serious symptoms, and the severity increased with the dose. : those who have a cold, fever or cough or live with someone with these symptoms). You should not drive after the infusion until you know how it will affect you. That's really great that she had that positive response though, seems worth it and hopeful for the rest of us! The infusion will be slowed or stopped if this occurs. In addition, dietary changes may help. Brush with a soft-bristle toothbrush or cotton swab twice a day. Also, try eating low-fiber, bland foods, such as white rice and boiled or baked chicken. This medicine contains alcohol and may cause some people to become drowsy, dizzy, or less alert than they are normally. We can get through it! You may experience a metallic taste or find that food has no taste at all. Treatment will be repeated every 28 days. A Quick Guide to the Best Types of Earrings for Sensitive Ears, 7 Useful Tips For A Wonderful Christmas Lights Decoration For Your Commercial Property. So I am sorry to confirm what you already know - the Taxotere is s*** and much more agressive than the FEC but you will get to the end of it. Some medicines are given by mouth as pills while others are given through an IV. WebDocetaxel (Taxotere; Rhne-Poulenc Rorer, Antony, France) is a semisynthetic taxoid that is an inhibitor of microtubule depolymerization. Lawsuits are being filed by women who were prescribed Taxotere to treat their breast cancer and later suffered eye damage. 5-star reviewed medical and legal information site. I was on taxotere and idI was on taxotere and id have my treatments on monday, and wednesday & thursdays were my bad days. I know it is really hard to go back when you know how rough it will make you feel-I tried to look at as a bad dose of flu( a normal person problem)No one would expect you to get out of bed with flu. I am on infusion 5 day 7. Make a list of your medications. Researchers think docetaxel plus the solvent in the infusion, polysorbate 80, may contribute to allergic reactions. Reactions can occur immediately after a patient receives the drug or days later. Update your browser for more security, speed and compatibility. Chemotherapy drugs are powerful and can take a toll on the body. Docetaxel may cause severe lack or loss of strength, which can last a few days up to several weeks. Even if it is to moan. If you would like to speak with a Drugwatch representative, please call 888-645-1617, "Drugwatch opened my eyes to the realities of big pharmacy. I know how awful Chemo is and I have been lucky that I haven't too many bad side effects I have delt with them as I got them. While it sounds harmless enough, constantly tearing eyes can cause other health issues. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. Some doctors may prescribe an anticonvulsive drug called gabapentin to help reduce symptoms. The medication causes fluid buildup in the limbs and around the heart and lungs. Paracetamol Ibuprofen/codiene didn't work. information highlighted below and resubmit the form. One of the most major Taxotere side effects is epiphora or, in simple terms, watery eyes. It can be anywhere from the 50s to 90s. Chart 2. If docetaxel does not work or stops working, cabazitaxel (Jevtana) may be used. This product is available in the following dosage forms: There is a problem with Mayo Clinic does not endorse companies or products. If this were to happen, the only fix is an invasive surgery. It took about 16 weeks from the last infusion to completely resolve in some patients. You may also feel irritable, dizzy, or short of breath. Each cycle lasts 3 weeks (21 days), so it takes about 3 months. Thanks for being such a grand support for her. Taxotere frequently triggers infusion reactions, according to Ho and Mackey. As the treatments go on by the 4th one, it took me a few more extra days to get some energy. WebAnswer (1 of 12): I lived in the LA area all my life64 years. You may also need to take your temperature at home during your treatment to stay on top of fevers. I can smell but can't taste anything! Your physician will order lab tests throughout your treatment to keep an eye on your levels. Taxotere is administered on days 1, 8 and 15 (rate: 1 hour). It, like other chemotherapy medications, can have severe side effects. Retrieved from, Karafiath, S. et al. The most common side effects are blood disorders and fluid retention, which occurred in 64% to 96% of people in clinical trials. You could talk to your doctor about your concerns and see if they can give you a lower dose if necessary?They also have pills for most things-I was told that they could probably help with everything but the tiredness. After starting docetaxel, many men experience the improvements in disease-related symptoms, including pain, fatigue and loss of bad days. So always stay in touch with the team.. Im out now on antibiotics.. Docetaxel can cause your body to hold too much fluid, which can be a serious side effect. But, according to the medication label, the chemotherapy drug has a few common side effects. These typically occur within minutes or hours of receiving the chemotherapy drug. Drugwatch's trusted legal partners support the organization's mission to keep people safe from dangerous drugs and medical devices. She is on this dose denseShe is on this dose dense regiment; every two weeks; 4 rounds of AC followed by 4 rounds of Taxol (and I think it's five day after Nuelasta shots). bad thanksgivings. But I'm on SSP and we can't afford to have him stay at home every time I feel ****. A week later and I still can't get out of bed! However on week 3 of the cycle got more or less back to normal before the next onslaught. The reason being is that most fatal vehicle collisions tend to happen on Saturdays. But, compared to other breast cancer therapy agents, docetaxel has a higher risk of febrile neutropenia, according to Ho and Mackey. It is also used together with other medicines (eg, cyclophosphamide, doxorubicin) to treat node-positive breast cancer that can be removed by surgery. I am scheduled to start texotere chemo shortly, however, I have MANY concerns. Doctors attribute the condition to canalicular stenosis caused by Taxotere. In addition to skin problems, docetaxel can cause separation of the nail from the nail bed, splintering, abnormal thickening and nail infections. health information, we will treat all of that information as protected health Review our editorial policy to learn more about our process for producing accurate, current and balanced content. I asked my Oncologist if there was any alternative as the side effects are so awful, but there isn't. Docetaxel interferes with the function of microtubules, resulting in inactive microtubule bundles, causing cells to die. WebSymptoms tend to develop a few days after treatment starts and include: the inside of your mouth feeling sore, as if you've burned it by eating very hot food mouth ulcers, which can become infected discomfort when eating, drinking and/or talking a dry mouth reduced sense of taste bad breath Tell your care team if you have any of these problems. 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